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Related Concept Videos

Adrenal Gland Disorders01:27

Adrenal Gland Disorders

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Adrenal gland disorders manifest when the production of adrenal hormones deviates from the norm, resulting in either excessive or insufficient concentrations.
Adrenal insufficiency, characterized by insufficient cortisol and aldosterone production, leads to conditions like Addison's disease. This disorder, affecting the adrenal cortex, exhibits symptoms such as skin bronzing, dehydration, low blood pressure, fatigue, and weight loss. Congenital adrenal hyperplasia, a genetic ailment causing...
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Hormones of the Adrenal Glands01:31

Hormones of the Adrenal Glands

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Adrenal hormones play a pivotal role in maintaining the body's electrolyte balance and orchestrating responses to stress, showcasing the intricate functions of the adrenal cortex and medulla.
The adrenal cortex, a powerhouse of hormone synthesis, generates over two dozen corticosteroid hormones. The zona glomerulosa produces mineralocorticoids, exemplified by aldosterone, influencing the electrolyte composition of body fluids. The synthesis of glucocorticoids such as cortisol and...
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Hormonal Regulation01:33

Hormonal Regulation

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Anatomy of the Adrenal Glands01:17

Anatomy of the Adrenal Glands

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The adrenal or supra-renal glands, situated above the kidneys and aligned with the twelfth rib, are paired pyramid-shaped structures crucial for the body's stress response. During stress, these glands secrete hormones vital for adaptive physiological reactions.
These glands possess a distinctive yellow tinge due to the stored cholesterol and fatty acids required for hormone synthesis. They are encased in a fibrous capsule and cushioned by fat.
The adrenal gland comprises two distinct...
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Adrenergic Agonists: Therapeutic Uses01:30

Adrenergic Agonists: Therapeutic Uses

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Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
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Adrenergic Antagonists: ɑ and β-Receptor Blockers01:31

Adrenergic Antagonists: ɑ and β-Receptor Blockers

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Third-generation β-blockers, such as labetalol and carvedilol, represent a significant advancement in managing cardiovascular conditions. Unlike conventional β-blockers, which can induce peripheral vasoconstriction, third-generation drugs block α1 adrenoceptors. This promotes vasodilation through several mechanisms, such as increased nitric oxide production, inhibition of calcium ion entry, opening of potassium ion channels, and antioxidant action. Labetalol, for instance, is...
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Related Experiment Video

Updated: Aug 15, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Adrenal disorders in pregnancy.

Adina F Turcu1, André Lacroix2

  • 1Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, USA. aturcu@umich.edu.

Reviews in Endocrine & Metabolic Disorders
|January 2, 2023
PubMed
Summary

Diagnosing and managing adrenal disorders in pregnant women is difficult due to overlapping symptoms and limited research. This collection offers expert insights for healthcare providers on pregnancy-related adrenal pathology.

Keywords:
AdrenalAdrenal insuficiencyHypertensionPregnancySteroids

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Area of Science:

  • Endocrinology
  • Obstetrics
  • Reproductive Medicine

Background:

  • Understanding of adrenal disorders in pregnancy is limited by overlapping symptoms, infrequent cases, and scarce research.
  • Lack of pregnancy-specific adrenal hormone reference ranges complicates diagnosis and management.
  • Adrenal conditions during pregnancy present unique clinical challenges.

Purpose of the Study:

  • To provide a comprehensive overview of current knowledge on adrenal disorders in reproductive-age women, with a focus on pregnancy.
  • To consolidate expert insights into a valuable resource for clinicians managing pregnancy-related adrenal pathology.

Main Methods:

  • This thematic issue compiles review articles from leading experts in adrenal physiology and pathology.
  • Content focuses on current knowledge and clinical management strategies.

Main Results:

  • The issue addresses the challenges in diagnosing and managing adrenal disorders during pregnancy.
  • It highlights the need for pregnancy-specific hormonal calibrations and further research.

Conclusions:

  • This collection serves as a crucial clinical companion for healthcare providers dealing with pregnancy-related adrenal conditions.
  • It aims to enhance the care of reproductive-age women with adrenal disorders.