Related Experiment Video
Updated: Aug 15, 2025

Rigid Embedding of Fixed and Stained, Whole, Millimeter-Scale Specimens for Section-free 3D Histology by Micro-Computed Tomography
Published on: October 17, 2018
Is there a Need to Change the Basic Principles of Histology? Educational, Functional and Embryological Perspective
I Varga1, D Kachlík, M Csöbönyeiová
1Institute of Histology and Embryology, Faculty of Medicine, Comenius University in Bratislava, Slovak Republic. ivan.varga@fmed.uniba.sk.
Classifying tissues is challenging but essential for medical education and practice. The established four basic tissue types (epithelial, connective, muscle, nervous) remain highly relevant despite ongoing classification discussions.
Area of Science:
- Histology
- Pathology
- Medical Education
Background:
- Tissue classification is crucial for understanding biological structures and functions.
- Historically, tissue classifications have evolved, with varying uniformity across educational resources.
- The current standard histological classification identifies four basic tissue types.
Purpose of the Study:
- To emphasize the importance of a clear and relevant tissue classification system.
- To discuss the historical development and current uniformity of tissue classification.
- To evaluate the suitability of the established four-tissue-type classification for modern needs.
Main Methods:
- Review of historical and current histological and pathological literature.
- Analysis of the didactic and clinical relevance of established tissue classifications.
- Consideration of recent proposals for alternative classification systems.
Main Results:
- The histological classification into epithelial, connective, muscle, and nervous tissues is widely adopted.
- This classification demonstrates relevance for education, embryology, and clinical practice.
- New classification proposals require careful evaluation for their practical utility.
Conclusions:
- A clear, didactic, and clinically relevant tissue classification is indispensable.
- The current four-tissue-type system offers significant advantages for medical education and practice.
- Innovations in tissue classification should be approached cautiously to ensure they meet educational and clinical demands.
Related Concept Videos
Gastrulation
Tissues
Fixation and Sectioning
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...
Simple Staining Technique
Determination
Overview of Anatomy and Physiology

