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Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
Published on: May 25, 2020
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Contrast sensitivity in glaucoma patients with visual field defects at different locations
1Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, 82, Gumi-ro, 173 Beon-gil, Bundang-gu, Seongnam, Gyeonggi-do, 463-707, Korea.
Scientific Reports
|January 2, 2023
Summary
Contrast sensitivity (CS) is crucial for glaucoma patients. While CS correlates with visual field sensitivity (VFS) in advanced disease, it poorly reflects early-stage defects in single hemifields.
Area of Science:
- Ophthalmology
- Neuroscience
- Vision Science
Background:
- Contrast sensitivity (CS) is vital for vision-related quality of life in glaucoma patients.
- Glaucoma often causes progressive visual field (VF) defects, impacting daily functioning.
Purpose of the Study:
- To investigate the relationship between contrast sensitivity (CS) and visual field sensitivity (VFS) in primary open-angle glaucoma (POAG).
- To determine how hemifield location of VF defects influences the CS-VFS correlation.
Main Methods:
- Cross-sectional study of 238 POAG patients.
- Simultaneous measurement of CS and 24-2 standard automated perimetry for VFS.
- Analysis of correlations based on VF defect location (superior, inferior, bi-hemifield, or none).
Main Results:
- Significant correlations between CS and VFS were found in the entire cohort.
- CS poorly represented VF defects in eyes with single superior or inferior hemifield defects.
- Eyes with bi-hemifield defects showed significant VFS-CS correlations at 0.3m, and in the inferior sector at 5m.
Conclusions:
- The correlation between CS and VFS is influenced by the extent of VF defects and testing distance.
- CS may not accurately reflect visual impairment in early, single-hemifield glaucoma defects.
- CS may be a more reliable indicator of visual disability in patients with bi-hemifield defects.
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