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Evaluation of apparent diffusion coefficient of two-dimensional BLADE turbo gradient- and spin-echo

Akiko Ohki¹, Hajime Sagawa^2,3, Mami Iima^4,5

¹Division of Clinical Radiology Service, Kyoto University Hospital, 54 Kawaharacho, Shogoin, Sakyo-Ku, Kyoto, 6068507, Japan. oki.akiko.omp@osaka-u.ac.jp.

Radiological Physics and Technology

|January 3, 2023

Abstract:

This study aimed to evaluate the reliability of apparent diffusion coefficient (ADC) values generated with two-dimensional turbo gradient- and spin-echo with BLADE trajectory diffusion-weighted imaging (TGSE-BLADE-DWI) sequence using a breast diffusion phantom. TGSE-BLADE-DWI and single-shot spin-echo echo-planar imaging (SS-EPI-DWI) were performed using a 3.0 T magnetic resonance imaging scanner. Concordance rates of ADC values and the signal-to-noise ratio (SNR) were compared between TGSE-BLADE-DWI and SS-EPI-DWI. TGSE-BLADE-DWI provided a higher concordance rate for ADC values than SS-EPI-DWI when b-values > 2000s/mm² and a slice thickness of 1 mm were used. TGSE-BLADE-DWI showed less image distortion than SS-EPI-DWI. The SNR of TGSE-BLADE-DWI was higher than that of SS-EPI-DWI, except at a number of excitations of 7 and a slice thickness of 1 mm. In conclusion, TGSE-BLADE-DWI can offer a better SNR, less distortion, and more reliable ADC measurements than SS-EPI-DWI in a breast phantom.

Keywords:

Apparent diffusion coefficient Breast Diffusion-weighted imaging Magnetic resonance imaging TGSE-BLADE-DWI Magnetic Resonance Imaging Diffusion-Weighted Imaging Image Distortion Signal-to-Noise Ratio

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