Simplified Meal Announcement Versus Precise Carbohydrate Counting in Adolescents With Type 1 Diabetes Using the...

Area of Science:

• Endocrinology
• Metabolic Diseases
• Pediatric Diabetes Management

Background:

• Type 1 diabetes (T1D) management in adolescents requires effective glucose control strategies.
• The MiniMed 780G system offers advanced automated insulin delivery features.
• Accurate carbohydrate counting is crucial but can be challenging for some users.

Purpose of the Study:

• To compare glucose control in adolescents with T1D using the MiniMed 780G system with simplified meal announcement versus precise carbohydrate counting.
• To evaluate the efficacy of simplified meal settings in achieving glycemic targets.

Main Methods:

• A randomized controlled trial involving 34 adolescents (12-18 years) with T1D.
• Participants were assigned to either a simplified fixed carbohydrate amount group (fix group) or a precise carbohydrate counting group (flex group) for 12 weeks.
• Primary endpoint was time in range (TIR); secondary endpoints included HbA1c and other glycometrics.

Main Results:

• The flex group achieved a significantly higher time in range (TIR) of 80.3% compared to the fix group's 73.5% (P=0.043).
• Time spent with glucose levels above 250 mg/dL was lower in the flex group (P=0.012).
• No significant differences were observed in HbA1c, time below range, or time between 180-250 mg/dL between the groups.

Conclusions:

• Adolescents using the MiniMed 780G system with simplified meal announcements can meet international glycemic control targets.
• Simplified meal settings present a valuable alternative for T1D patients who find precise carbohydrate counting difficult.
• Carbohydrate counting skills remain important for optimizing outcomes with the MiniMed 780G system.