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Advances on microfluidic paper-based electroanalytical devices.

Joseph Benjamin Holman¹, Zhengdi Shi¹, Adeola A Fadahunsi¹

¹School of Information Science and Technology, University of Science and Technology of China, Hefei, Anhui 230027, China.

Biotechnology Advances

|January 5, 2023

Summary

This summary is machine-generated.

Microfluidic paper-based electroanalytical devices (μPEDs) offer advanced capabilities for sample preprocessing and analysis. These paper-based sensors provide comparable performance to conventional devices, with enhanced features for diverse applications.

Keywords:

Electrochemical sensor Paper-based microfluidics Point-of-care ePAD μPEDs

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Area of Science:

Electrochemistry
Analytical Chemistry
Materials Science

Background:

Microfluidic paper-based electroanalytical devices (μPEDs) have evolved significantly since their inception.
Advancements in hydrophobic barriers and electrode fabrication have enabled diverse material incorporation and improved performance.
μPEDs offer benefits like pumpless fluidic transport, component separation, and reagent storage for automated sample preprocessing.

Purpose of the Study:

To review microfluidic paper-based electroanalytical devices (μPEDs).
To summarize the characteristics and functionalities of μPEDs, including separation, fluid flow control, and storage.
To outline conventional and emerging fabrication and modification approaches for μPEDs.
To examine recent applications of μPEDs in biomedicine, environmental monitoring, and food/water safety.

Main Methods:

Literature review of microfluidic paper-based electroanalytical devices (μPEDs).
Analysis of fabrication and modification techniques for μPEDs.
Examination of μPED applications across various fields.

Main Results:

μPEDs demonstrate performance comparable to conventional devices.
μPEDs facilitate automated sample preprocessing through features like pumpless fluid transport and integrated reagent storage.
Recent applications highlight the versatility of μPEDs in critical areas such as biomedicine and environmental safety.

Conclusions:

μPEDs represent a significant advancement in analytical device technology.
The review covers key aspects of μPEDs, from fabrication to application.
Addressing current limitations and challenges will further enhance the potential of μPEDs.