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Updated: Aug 15, 2025

Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen
Published on: June 3, 2018
An ultra-sensitive and selective electrochemical sensor based on GOCS composite and ion imprinted polymer for the
Fengqin Yin1, Yeling Mo1, Xueting Liu1
1School of Health Science and Engineering, Shanghai Engineering Research Center of Food Rapid Detection, University of Shanghai for Science and Technology, Shanghai, China.
Abstract:
An ultra-sensitive and selective electrochemical sensor was proposed through the combination of carbon disulfide-functionalized graphene oxide (GOCS) composite with high conductivity and cadmium ion-imprinted polymer (IIP). Using pyrrole as the functional monomer and Cd2+ as the template ion, the IIP was formed by in situ electropolymerization on GOCS composite. Under the optimized experimental conditions, the sensor exhibited a good linear relationship in the range of 0.5-50 μg/L Cd2+ concentration, with the lowest detection limit of 0.23 μg/L. The sensor exhibited not only good selectivity for the determination of Cd2+, but also good repeatability with current response remaining 87.6 % after four cycles. Furthermore, the sensor exhibited similar sensing performance in lettuce, orange and peach with recovery ranging from 82.6 % to 110.63 %. This work is expected to provide an electrochemical sensor with excellent selectivity, good stability and sensitivity for the detection of trace amounts of Cd2+ in real samples.
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