Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teratogenicity01:07

Teratogenicity

2.6K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.6K
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

34.9K
Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
34.9K
Fetal Circulation01:14

Fetal Circulation

1.2K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
1.2K
CRISPR01:59

CRISPR

52.6K
Genome editing technologies allow scientists to modify an organism’s DNA via the addition, removal, or rearrangement of genetic material at specific genomic locations. These types of techniques could potentially be used to cure genetic disorders such as hemophilia and sickle cell anemia. One popular and widely used DNA-editing research tool that could lead to safe and effective cures for genetic disorders is the CRISPR-Cas9 system. CRISPR-Cas9 stands for Clustered Regularly Interspaced...
52.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Gestational Exposure to 10 Classes of Priority Chemicals and Birth Outcomes in the ECHO Cohort.

JAMA network open·2026
Same author

Handling of multicohort data in pooled analysis of environmental exposures: confounding by cohort of the relationship between perfluoroalkyl substances and birthweight in the ECHO Program.

American journal of epidemiology·2026
Same author

Subfecundity, Infertility Treatment, and Child Neurodevelopment.

JAMA network open·2026
Same author

Prenatal exposure to organophosphate ester flame retardants and plasticizers and maternal immune responses in three ECHO cohorts.

Environmental research·2026
Same author

MRI-based dental maturity in newborns reflects prenatal exposures and predicts timing of primary tooth eruption.

bioRxiv : the preprint server for biology·2026
Same author

slideimp: efficient imputation of DNA methylation data.

Bioinformatics (Oxford, England)·2026
Same journal

Navigating Uncertainty: Facilitating Parent-Child Conversations about Immigration Enforcement-Related Family Separation.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Trauma-Informed Principles on Informing Caregivers of Referrals to Child Protective Services.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Editorial: Parental Support Increases Food Volume in Childhood Avoidant/Restrictive Food Intake Disorder, But What About Food Variety?

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Editorial: Bringing Care Home: Intensive Community Services as a Viable Alternative to Adolescent Psychiatric Hospitalization.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Educational Attainment Polygenic Scores and School Performance in Adolescents With Psychiatric Disorders: A Population-Based Analysis of 86,122 Individuals From the iPSYCH2015 Case-Cohort.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
Same journal

Editorial: Beyond Risk: The Case for Protective Factors in Adolescent Suicide.

Journal of the American Academy of Child and Adolescent Psychiatry·2026
See all related articles

Related Experiment Video

Updated: Aug 15, 2025

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
14:40

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

9.5K

Fetal Programming and Public Policy.

Vivette Glover1, Thomas G O'Connor2, Kieran J O'Donnell3

  • 1Imperial College London, United Kingdom.

Journal of the American Academy of Child and Adolescent Psychiatry
|January 7, 2023
PubMed
Summary
This summary is machine-generated.

Fetal programming explains how the prenatal environment influences lifelong health. Early life conditions can lead to lasting health effects, impacting cardiovascular and neural development.

More Related Videos

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

730
Mouse In Vivo Placental Targeted CRISPR Manipulation
07:39

Mouse In Vivo Placental Targeted CRISPR Manipulation

Published on: April 14, 2023

2.7K

Related Experiment Videos

Last Updated: Aug 15, 2025

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
14:40

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

9.5K
Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring
06:11

Author Spotlight: Exploring the Long-Term Health Impacts of Intracytoplasmic Sperm Injection on Offspring

Published on: May 17, 2024

730
Mouse In Vivo Placental Targeted CRISPR Manipulation
07:39

Mouse In Vivo Placental Targeted CRISPR Manipulation

Published on: April 14, 2023

2.7K

Area of Science:

  • Developmental biology
  • Public health
  • Epigenetics

Background:

  • Fetal programming is a key concept in the developmental origins of health and disease (DOHaD).
  • It posits that the prenatal environment shapes long-term health outcomes.
  • This theory is supported by findings linking low birth weight to later cardiovascular disease.

Discussion:

  • The fetus adapts to environmental exposures during gestation.
  • These adaptations can alter biological systems, affecting health throughout life.
  • The concept has expanded beyond cardiometabolic issues to include neural and psychiatric phenotypes.

Key Insights:

  • Prenatal environment significantly impacts postnatal health and disease risk.
  • Early life interventions can mitigate long-term health consequences.
  • Fetal programming offers a framework for understanding chronic disease etiology.

Outlook:

  • Further research into the molecular mechanisms of fetal programming is needed.
  • Translating DOHaD principles into public health strategies is crucial.
  • Understanding fetal programming can inform preventative healthcare approaches.