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Systemic Heparinization After Neuraxial Anesthesia in Vascular Surgery: A Retrospective Analysis.

Dana Archibald1, Thomas Stambulic2, Morgan King2

  • 1Department of Anesthesiology and Perioperative Medicine, Queen's University, Kingston, Ontario, Canada.

Journal of Cardiothoracic and Vascular Anesthesia
|January 7, 2023
PubMed
Summary

Most vascular surgery patients received systemic heparinization within 1 hour of neuraxial anesthesia (NA), aligning with guidelines to prevent spinal hematoma (SH). No SHs occurred in this study, suggesting current practices may be safe.

Keywords:
neuraxial anesthesiaretrospective analysisspinal hematomasystemic heparinvascular surgery

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Area of Science:

  • Anesthesiology
  • Vascular Surgery
  • Pain Medicine

Background:

  • Current guidelines recommend a 1-hour interval between neuraxial anesthesia (NA) and systemic heparinization to minimize spinal hematoma (SH) risk.
  • The safety and adherence to this interval in vascular surgery patients require characterization.

Purpose of the Study:

  • To determine the time interval between NA and systemic heparinization in vascular surgery patients.
  • To assess the incidence of SH and estimate the risk of SH formation.

Main Methods:

  • Retrospective analysis of 127 vascular surgery patients who received NA between April 2012 and April 2022.
  • Data collected included time from NA to heparin, heparin dose, surgery length, NA difficulty, and patient demographics.

Main Results:

  • The average time from NA to heparin administration was 42.8 ± 22.1 minutes.
  • 83.7% of patients received heparin within 1 hour of NA.
  • No spinal hematomas were reported during the study period.

Conclusions:

  • The majority of vascular surgery patients in this academic center received heparin within the recommended 1-hour interval after NA.
  • Further research is needed to validate these findings in diverse settings.