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Nanosphere Structures Using Various Materials: A Strategy for Signal Amplification for Virus Sensing
Sjaikhurrizal El Muttaqien1,2, Indra Memdi Khoris1, Sabar Pambudi2
1Research Institute of Green Science and Technology, Shizuoka University, 836 Ohya Suruga-ku, Shizuoka 422-8529, Japan.
Sensors (Basel, Switzerland)
|January 8, 2023
Summary
This review highlights 3D nanospheres for developing sensitive biosensors for pathogenic virus detection. These nanomaterials offer signal amplification for rapid, portable diagnostic platforms, addressing key challenges in the field.
Area of Science:
- Materials Science
- Biotechnology
- Nanotechnology
Background:
- Nanomaterials are crucial in sensing research, with 3D nanomaterials significantly advancing biomedical applications.
- However, their potential in biosensors for pathogenic virus detection remains underexplored.
Purpose of the Study:
- This review focuses on 3D nanospheres for pathogenic virus detection biosensors.
- It explores their application in various sensing techniques and signal amplification strategies.
Main Methods:
- The review discusses 3D nanosphere structures made from polymers, carbon, silica, and metal-organic frameworks (MOFs).
- It examines their role in enhancing sensitivity for virus detection.
Main Results:
- 3D nanospheres provide a versatile platform for rapid and portable biosensor development.
- Signal amplification strategies using different nanosphere compositions lead to high-sensitivity virus detection.
Conclusions:
- 3D nanosphere-based biosensors show great promise for sensitive and rapid pathogenic virus detection.
- Challenges such as nanomaterial toxicity and commercialization need further attention for future development.
