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Assessment and management of asthma exacerbations in an emergency department unit

Konstantinos Douros1, Dafni Moriki2, Olympia Sardeli2

  • 13rd Department of Pediatrics, "Attikon" University Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece; costasdouros@gmail.com.

Allergologia Et Immunopathologia
|January 9, 2023
PubMed

Insights

The Pediatric Respiratory Assessment Measure (PRAM) score effectively predicts hospitalization risk in children with mild-moderate asthma exacerbations. Higher initial PRAM scores indicate increased risk, while improvement suggests a lower risk.

Area of Science:

  • Pediatric Pulmonology
  • Asthma Management
  • Clinical Assessment Tools

Background:

  • The Pediatric Respiratory Assessment Measure (PRAM) score is a validated tool for assessing pediatric asthma exacerbations.
  • Mild-to-moderate asthma exacerbations in children require effective assessment tools to predict outcomes.

Purpose of the Study:

  • To evaluate the risk of hospitalization in children with mild-moderate asthma exacerbations.
  • To determine the association between the PRAM score and hospitalization risk when treated with salbutamol via metered-dose inhaler and spacer (MDI/S).

Main Methods:

  • A cohort of children aged 3-16 years with mild-moderate asthma exacerbations was studied.
  • Participants received oral prednisolone and salbutamol via MDI/S.
  • The initial and improved PRAM scores were analyzed for their association with hospitalization.

Main Results:

  • Fifty pediatric patients were included in the study.
  • A higher initial PRAM score was significantly associated with increased odds of hospitalization (OR: 18.91, P = 0.005).
  • Improvement in the PRAM score was associated with decreased odds of hospitalization (OR: 0.52, P = 0.032).

Conclusions:

  • The PRAM score is a reliable tool for assessing asthma exacerbation severity in children.
  • PRAM score dynamics can effectively predict the need for hospitalization in pediatric asthma patients.
Abstract

Keywords:
PRAMasthmachildrenmetered-dose inhalersalbutamolspacer

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