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Efficacy of Virtual Care for Depressive Disorders: Systematic Review and Meta-analysis
Crystal Edler Schiller1, Julianna Prim1, Anna E Bauer1
1Department of Psychiatry, University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Virtual interventions effectively treat depression compared to control groups. Evidence suggests virtual and in-person treatments offer similar outcomes for depressive disorders.
Area of Science:
- Mental Health
- Digital Health
- Psychiatry
Background:
- The COVID-19 pandemic increased depression rates and the need for remote mental healthcare.
- Evidence supporting virtual interventions for mental health remains unclear.
Purpose of the Study:
- To evaluate the efficacy of virtual interventions for depressive disorders.
- To compare virtual interventions against no treatment, treatment as usual (TAU), and attention control.
- To compare virtual interventions against in-person interventions.
Main Methods:
- Systematic review of randomized controlled trials (RCTs) from PubMed, EMBASE, and PsycINFO (2010-2021).
- Included adults with depressive disorders receiving virtual interventions, assessed with validated depression measures.
- Analyzed remission, response, and depression severity using odds ratios (ORs) and standardized mean differences (SMDs).
Main Results:
- Virtual interventions showed higher odds of remission and lower symptom severity compared to waitlist controls.
- Virtual interventions were superior to treatment as usual (TAU) and attention control groups.
- No significant difference in outcomes between in-person and virtual interventions was found.
Conclusions:
- Virtual interventions are efficacious for treating depressive disorders compared to various control conditions.
- The strength of evidence indicates in-person interventions do not significantly outperform virtual ones for depression.
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