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Updated: Aug 14, 2025

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Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
Published on: May 27, 2022
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Extraction techniques for bioactive compounds of cannabis.
Aitor Sainz Martinez1, Olga Lanaridi1, Kristof Stagel1
1Institute of Applied Synthetic Chemistry, TU Wien, Getreidemarkt 9/163, Vienna, Austria. katharina.schroeder@tuwien.ac.at.
Natural Product Reports
|January 10, 2023
Summary
Cannabis, an ancient crop, is regaining prominence for its non-intoxicating cannabinoids like CBD and CBN. Research focuses on extracting these beneficial compounds from cannabis for various applications.
Area of Science:
- Ethnobotany
- Pharmacognosy
- Medicinal Chemistry
Background:
- Cannabis has a long history of use in civilization for fiber, nutrition, and medicine.
- Decline in traditional uses due to synthetic materials and focus on THC's psychoactive properties.
- Resurgence driven by non-intoxicating cannabinoids like cannabidiol (CBD) and cannabinol (CBN), fueling a new market.
Purpose of the Study:
- To provide a historical overview of cannabis.
- To explore cannabis classification, nomenclature, and chemical constituents.
- To review extraction methods for valuable bioactive compounds from cannabis.
Main Methods:
- Literature review of historical records and scientific publications.
- Analysis of cannabis plant classification and nomenclature systems.
- Synthesis of information on chemical profiles and extraction techniques.
Main Results:
- Cannabis has diverse historical applications, including medicinal uses.
- Identification of key non-intoxicating cannabinoids (CBD, CBN) driving current interest.
- Significant advancements in the extraction of bioactive compounds from cannabis.
Conclusions:
- Cannabis holds significant potential beyond its historical uses.
- Continued research into extraction and application of beneficial cannabinoids is crucial.
- Future research should focus on optimizing extraction and exploring novel applications.

