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Updated: Aug 14, 2025

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
Published on: February 7, 2017
Diastereomeric multi-chiral pendant groups: Their key role in stimuli-responsive polymeric responses
Rafael Rodríguez1, Elena Rivadulla-Cendal1, Emilio Quiñoá1
1Centro Singular de investigación en Química Biolóxica e Materiais Moleculares (CiQUS) e Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
Abstract:
Chiral information transmission in helical polymers bearing multi-chiral pendant groups is usually determined by the absolute configuration of the first chiral center. The second chiral residue usually has low-to-null influence in the macromolecular handedness of the polymer, due to its remote position respect to the polyene main chain. Here, we demonstrate how the stimuli responsive properties of diastereomeric polymers, obtained by changing the absolute configuration of the second chiral center, are different due to the unlike properties of diastereoisomers.
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Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...

