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Related Experiment Video

Updated: Aug 14, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1
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Mpox (Monkeypox) Presenting as Cervical and Vulvar Disease.

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  • 1Gynaecology Oncology Unit, Institute of Women's Health José Botella Llusiá, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC), School of Medicine, Complutense University, Institute of Women's Health José Botella Llusiá, San Carlos Clinical Hospital, Hospital Clínico San Carlos, Internal Medicine-Infectious Diseases, IdISSC, CIBERINFEC, Unidad Docente Centro-Gerencia Atención Primaria, and Hospital Clínico San Carlos, Anatomic Pathology, Madrid, Spain.

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Summary

Mpox can affect women

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Area of Science:

  • Virology
  • Dermatology
  • Gynecology

Background:

  • The mpox (formerly monkeypox) outbreak beginning in May 2022 has primarily affected men, with women comprising less than 1% of Europe's 23,465 reported cases.
  • Genital lesions are common in mpox, and in women, have typically been observed on the vulva.

Observation:

  • A case study details a 28-year-old woman with mpox virus infection confirmed by PCR.
  • Her sole symptoms were cervical and vulvar lesions, with no other clinical signs or co-existing sexually transmitted diseases.

Findings:

  • Mpox virus infection can manifest with cervical lesions in women.
  • The observed lesions in this case resolved spontaneously within two weeks.

Implications:

  • Gynecologists must be aware of mpox's potential to cause cervical lesions for accurate diagnosis.
  • Early identification of mpox in women is crucial for controlling disease transmission during the current epidemic.