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Updated: Aug 14, 2025

Pretargeted Radioimmunotherapy Based on the Inverse Electron Demand Diels-Alder Reaction
Published on: January 29, 2019
Status of α-emitter Radioimmunoconjugates for Targeted Therapy
Rabiei Mobina1, Ahmad Reza Vaez Alaei2, Hassan Yousefnia3
1Nuclear Engineering School, Islamic Azad University Shahrood Branch, Shahrud, Iran.
Abstract:
This minireview describes the global situation of ongoing research and development and the clinical application of alpha emitter labeled immunoconjugates with various alpha emitters with an overview of the future trends. The potentially helpful alpha emitter radioisotopes for medical applications, chelators, and immunomolecules of interest for future alpha radioimmunotherapy are discussed. Challenges and some suggested future works on chelators are also presented.
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