Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Nephrotic Syndrome II : Assessment and Medical Management

Nephrotic Syndrome II : Assessment and Medical Management

IntroductionNephrotic syndrome is a kidney disorder marked by excessive protein loss in the urine, leading to various systemic complications. This condition often results from damage to the glomeruli—the kidney's filtering units—causing proteinuria, low blood protein levels, and fluid retention. Understanding the assessment, diagnosis, and management of nephrotic syndrome is essential for effective treatment and prevention of further kidney damage.AssessmentPatient History: Document...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Acute retinal artery occlusions.

Handbook of clinical neurology·2026

Same author

Clinical and Demographic Predictors of Optic Neuritis Subtype.

Neuro-ophthalmology (Aeolus Press)·2026

Same author

Artificial Intelligence-Based Prognostic Models for Postoperative Outcomes in Vitreoretinal Surgery: A Systematic Review and Meta-Analysis.

Ophthalmology. Retina·2026

Same author

Visual Field Testing: The Key to Localizing Afferent Visual Pathway Lesions.

Neurologic clinics·2026

Same author

Update on Acute Retinal Arterial Ischemic Disorders.

Neurologic clinics·2026

Same author

Ischemic optic neuropathy with semaglutide: global observational analysis of sex- and formulation-specific risk.

The British journal of ophthalmology·2026

Search research articles

Related Experiment Video

Updated: Aug 14, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Optic neuritis: current challenges in diagnosis and management.

Etienne Benard-Seguin¹, Fiona Costello^1,2

¹Department of Surgery, Section of Ophthalmology.

Current Opinion in Neurology

|January 11, 2023

Summary

This review details optic neuritis (ON) subtypes, focusing on clinical presentation, imaging, and serology. Early diagnosis of conditions like MOGAD and NMOSD is crucial to prevent vision loss and disability.

More Related Videos

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Published on: September 4, 2021

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

Related Experiment Videos

Last Updated: Aug 14, 2025

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Dynamic Visual Tests to Identify and Quantify Visual Damage and Repair Following Demyelination in Optic Neuritis Patients

Published on: April 14, 2014

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Quantification of Optic Nerve Cross Sectional Area on MRI: A Novel Protocol using Fiji Software

Published on: September 4, 2021

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Optic Nerve Sheath Point of Care Ultrasound: Image Acquisition

Published on: August 18, 2023

Area of Science:

Neuro-ophthalmology
Neuroimmunology

Background:

Optic neuritis (ON) is optic nerve inflammation with diverse causes.
ON can be sporadic or associated with central nervous system (CNS) inflammatory diseases like multiple sclerosis (MS), neuromyelitis optic spectrum disorders (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).

Approach:

This review synthesizes current knowledge on ON subtypes.
It covers clinical course, neuroimaging features, and serological profiles.
Diagnostic challenges and treatment strategies are discussed.

Key Points:

ON subtypes associated with MS, NMOSD, and MOGAD have distinct antibody profiles and imaging characteristics, despite overlapping clinical symptoms.
Accurate diagnosis relies on a detailed patient history and comprehensive physical examination.
Different ON subtypes necessitate varied treatment approaches and have distinct prognoses.

Conclusions:

Timely identification of MOGAD and NMOSD is critical to avert permanent vision impairment and neurological deficits.
Understanding ON subtypes guides appropriate management and improves patient outcomes.