Comparison of Refractive Prediction Accuracy With Three Optical Devices

Area of Science:

• Ophthalmology
• Biomedical Engineering
• Optical Metrology

Background:

• Cataract surgery requires precise biometry for accurate refractive outcomes.
• Several optical biometers are available, each with varying performance characteristics.
• Comparing the accuracy and reliability of these devices is crucial for clinical decision-making.

Purpose of the Study:

• To compare the refractive prediction accuracy of the OA-2000, Anterion, and IOLMaster 500 biometers.
• To evaluate the axial length (AL) measurement acquisition rates of these devices in cataract patients.
• To assess the agreement of biometric parameters obtained from the three devices.

Main Methods:

• Patients with cataract underwent scanning with OA-2000, Anterion, and IOLMaster 500.
• Axial length (AL) measurement success rates were calculated and compared using chi-square tests.
• Bland-Altman analysis assessed agreement for keratometry (K1, K2), anterior chamber depth (ACD), and AL.
• Refractive prediction accuracy was evaluated using predictive error (PE) with four standard formulas.

Main Results:

• OA-2000 and Anterion showed significantly higher AL acquisition rates (97.35%, 94.70%) compared to IOLMaster 500 (84.82%).
• Good agreement was observed between the three devices for K1, K2, ACD, and AL measurements.
• No statistically significant differences were found in refractive prediction accuracy (MAE, MedAE, PE within ±0.50-1.00 D) among the devices.

Conclusions:

• OA-2000 and Anterion offer superior AL measurement acquisition rates compared to IOLMaster 500 in cataract patients.
• All three biometers demonstrate good agreement for key biometric parameters.
• Refractive prediction accuracy is comparable across the OA-2000, Anterion, and IOLMaster 500, suggesting reliable performance for surgical planning.