Platelet-rich plasma injection for empty nose syndrome: A case report

Area of Science:

• Otolaryngology
• Regenerative Medicine

Background:

• Empty nose syndrome (ENS) is a challenging condition following sinonasal surgery, often resulting from turbinate reduction.
• Symptoms include nasal dryness, pain, paradoxical obstruction, and crusting, significantly impacting quality of life.
• Current treatments have limitations, with surgical options posing predictability and complication risks.

Observation:

• This study explores platelet-rich plasma (PRP) injections as a novel therapeutic approach for ENS.
• Two patient cases with ENS were treated using PRP injections, a minimally invasive regenerative therapy.
• Efficacy was assessed via nasal endoscopy and patient-reported subjective questionnaires.

Findings:

• Platelet-rich plasma (PRP) injections demonstrated potential efficacy in managing Empty Nose Syndrome (ENS) symptoms.
• The treatment was observed to be a simple and less invasive alternative to traditional surgical interventions.
• Improvements in nasal function and symptom reduction were noted in the treated patients.

Implications:

• Platelet-rich plasma (PRP) offers a promising, minimally invasive therapeutic option for Empty Nose Syndrome (ENS).
• Further research into PRP's regenerative potential could refine treatment strategies for this debilitating condition.
• This approach may improve patient outcomes and reduce the need for complex surgical revisions in ENS management.