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A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
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Regional Antibiotic Delivery for Implanted Cardiovascular Electronic Device Infections

Moris Topaz1, Ehud Chorin2, Arie Lorin Schwartz2

  • 1Department of Cardiology, Sourasky Tel Aviv Medical Center, Tel Aviv, Israel; Emeritus Plastic Surgery Unit, Hillel Yaffe Medical Center, Hadera, Israel.

Journal of the American College of Cardiology
|January 11, 2023
PubMed
Summary

Continuous, in situ-targeted, ultrahigh concentration of antibiotics (CITA) offers a safe and effective alternative for treating pocket infections in patients with cardiovascular implantable electronic devices (pacemakers/defibrillators). This approach avoids device and lead extraction in many cases, reducing complications.

Keywords:
defibrillatorinfectionlead extractionpacemaker

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