Related Experiment Video

Updated: Aug 14, 2025

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression
08:58

Cystic Fibrosis Aggregate Biofilm Model to Study Infection-relevant Gene Expression

Published on: April 18, 2025

603

Cystic Fibrosis: Back to the Basics

Heather Myer, Sarah Chupita, Amy Jnah

    Neonatal Network : NN
    |January 11, 2023
    PubMed

    Keywords:
    back to basicsclinical manifestationscystic fibrosisepidemiologygeneticsmetabolicpathophysiologyrespiratorytherapeutic regimens

    More Related Videos

    Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study08:00

    Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study

    Published on: April 11, 2018

    10.8K
    Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice08:55

    Nasal Potential Difference to Quantify Trans-epithelial Ion Transport in Mice

    Published on: July 4, 2018

    7.8K

    Related Concept Videos

    Cystic Fibrosis: Pathogenesis01:23

    Cystic Fibrosis: Pathogenesis

    Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
    CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
    324
    Cystic Fibrosis: Management01:24

    Cystic Fibrosis: Management

    Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
    Sinus disease and chronic...
    210
    Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

    Chronic Obstructive Pulmonary Disease-II: Pathophysiology

    Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
    Chronic Inflammation
    2.9K
    Transcellular Transport of Solutes01:23

    Transcellular Transport of Solutes

    Transcellular transport of solutes is the movement of substances like monosaccharides and amino acids through polarized cells. This transport mechanism is primarily seen in epithelial and endothelial cells aided by membrane transport proteins such as channels and transporters. The tight junctions between these cells confine the membrane proteins to the two sides of the cell. The epithelial cells have distinct apical and basolateral domains. In contrast, the endothelial cells show the luminal...
    3.7K
    Chronic Pancreatitis I: Introduction01:24

    Chronic Pancreatitis I: Introduction

    The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
    Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
    Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
    132
    The Significance of Membrane Transport01:44

    The Significance of Membrane Transport

    The transport of solutes across the cell membrane is essential for metabolic processes, like maintaining cell size and volume, generating the action potential, exchanging nutrients and gases, etc. Membrane transport can be either passive or active. It can be simple diffusion, facilitated, or mediated transport aided by transport proteins such as transporters and channels.
    Transporters facilitate either an active or passive movement of solutes. They can allow a single-molecule transport down its...
    28.3K