Spontaneous coronary artery dissection in cutis laxa
Pia Frances Pemberton Charters1, Daniel Barnaby McKenzie, Jonathan Carl Luis Rodrigues
1Royal United Hospitals Bath NHS Foundation Trust, Bath, UK.
BJR Case Reports
|January 12, 2023
Summary
This case study presents a young female with Cutis Laxa who experienced acute coronary syndrome due to spontaneous coronary artery dissection (SCAD). CT coronary angiogram diagnosed SCAD, successfully treated with medication.
Area of Science:
- Cardiology
- Genetics
- Dermatology
Background:
- Cutis Laxa is a rare genetic connective tissue disorder characterized by inelastic skin.
- Cardiovascular complications are known in Cutis Laxa, but spontaneous coronary artery dissection (SCAD) has not been previously reported.
- SCAD is an infrequent cause of acute coronary syndrome, particularly in young women.
Observation:
- A 21-year-old female with Cutis Laxa presented with acute coronary syndrome.
- CT coronary angiogram revealed spontaneous coronary artery dissection (SCAD) of the right coronary artery.
- The patient was successfully managed with medical therapy.
Findings:
- This is the first reported case of SCAD in a patient with Cutis Laxa.
- CT coronary angiogram proved effective for diagnosing SCAD, avoiding risks associated with invasive procedures.
- Medical management was successful for SCAD in this patient.
Implications:
- Highlights a novel association between Cutis Laxa and SCAD.
- Suggests CT coronary angiogram as a valuable diagnostic tool for SCAD, especially in patients with connective tissue disorders.
- Emphasizes the importance of considering SCAD in young females presenting with acute coronary syndrome, even with rare underlying conditions.
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