Related Experiment Video
Updated: Aug 14, 2025

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Outcomes of Arterial Bypass for Posterior Circulation Atherosclerosis: A Case Series
Jeffrey Farooq1, Keaton Piper2, Elton Yeung3
1Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Insights
Arterial bypass surgery for posterior circulation atherosclerotic disease showed excellent outcomes and graft patency in 8 patients. This effective treatment option improved symptoms and functional status with no major complications.
Area of Science:
- Neurosurgery
- Vascular Surgery
- Neurology
Background:
- Extracranial-intracranial bypass is established for moyamoya disease and anterior circulation disease.
- Its efficacy in posterior circulation atherosclerosis requires further evaluation.
- Updated surgical techniques necessitate re-appraisal for refractory cases.
Purpose of the Study:
- To assess complications, graft patency, and outcomes of arterial bypass in posterior circulation intracranial atherosclerotic disease.
Main Methods:
- Retrospective review of perioperative records for bypass patients.
- Evaluation of clinical course and surgical outcomes.
Main Results:
- Eight patients underwent direct bypass using autologous occipital artery.
- All patients showed clinical improvement, with a significant decrease on the modified Rankin Scale.
- Graft patency was confirmed in 7 patients (full) and 1 patient (partial).
Conclusions:
- Posterior circulation arterial bypass offers excellent outcomes and no major complications for medically refractory intracranial atherosclerotic disease.
- This intervention is valuable for symptomatic posterior circulation disease.
- Larger studies are recommended for validation.
Background:
Extracranial-intracranial bypass is an effective treatment option for moyamoya disease and in well-selected cases of anterior circulation intracranial atherosclerotic disease; however, the effectiveness of bypass is less evident in posterior circulation atherosclerosis. Updated surgical techniques and clinical guidelines necessitate modern appraisal of arterial bypass for symptomatic patients with posterior circulation atherosclerotic disease who are refractory to medical management.
Objective:
To evaluate the complications, graft patency, and postoperative outcomes of arterial bypass for posterior circulation intracranial atherosclerotic disease.
Methods:
Perioperative records of consecutive bypass patients were retrospectively evaluated to determine the clinical course and surgical outcomes.
Results:
Arterial bypass was performed in 8 cases with a median age of 62 years. All 8 patients underwent direct bypass with an autologous occipital artery donor vessel. Recipient vessel selection varied on a case-by-case basis, with the superior cerebellar artery used in 4 cases, the posterior inferior cerebellar artery in 3 cases, and the anterior inferior cerebellar artery in 1 case. There were no significant intraoperative or postoperative complications. Postoperatively, all 8 patients displayed clinical improvement of their preoperative symptoms, with a significant decrease of 2.5 points on the modified Rankin Scale (P < .001). Postoperative imaging confirmed full graft patency in 7 patients and partial patency in 1 patient.
Conclusion:
Excellent postoperative outcomes and no major complications after posterior circulation arterial bypass for intracranial atherosclerotic disease highlight the utility of this intervention for the treatment of medically refractory or symptomatic posterior circulation intracranial atherosclerotic disease. Larger studies may be valuable to validate these findings.
Related Concept Videos
Peripheral Artery Disease V: Postoperative Nursing Management
Peripheral Artery Disease III: Interprofessional Care
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
The Arch of Aorta
Encircling the heart, the coronary arteries form a ring-like structure before...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Peripheral Artery Disease I: Introduction

