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Spt4 promotes cellular senescence by activating non-coding RNA transcription in ribosomal RNA gene clusters

Masaaki Yokoyama1, Mariko Sasaki1, Takehiko Kobayashi2

  • 1Laboratory of Genome Regeneration, Institute for Quantitative Biosciences (IQB), The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Cell Reports
|January 14, 2023
PubMed

Keywords:
CP: Cell biologyCP: Molecular biologySpt4budding yeastgenome instabilitylifespannon-coding RNA transcriptionrDNAsenescence

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