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Paf1 Counteracts transcriptional arrest to maintain rDNA stability during pol I elongation

Zijun Zhong1, Masaaki Yokoyama1, Takehiko Kobayashi2

  • 1Laboratory of Genome Regeneration, Institute for Quantitative Biosciences (IQB), The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-0032, Japan; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Cell Reports
|June 25, 2026
PubMed

Keywords:
CP: cell biologyCP: molecular biologyR-loopRNA polymerase IRNase Hgenome instabilitypaf1rDNAribosomal RNA genetop1torsional stress

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