Related Experiment Videos
Radiological features of systemic mast-cell disease
1Department of Diagnostic Radiology, Veterans Administration Medical Center, Louisville, Kentucky.
The British Journal of Radiology
|August 1, 1987
Summary
Radiological studies reveal bone and gastrointestinal changes in systemic mast-cell disease (SMCD). These findings aid in diagnosing SMCD and assessing its systemic spread.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Systemic mast-cell disease (SMCD) is a rare disorder.
- Mast cell infiltration and mediator release can affect various organs.
Purpose of the Study:
- To investigate radiological findings in patients with SMCD.
- To correlate radiological changes with disease manifestations.
Main Methods:
- Retrospective analysis of radiological studies in 23 SMCD patients.
- Evaluation of bone, gastrointestinal, and visceral organ involvement.
Main Results:
- Skeletal abnormalities were the most frequent radiological finding.
- Gastrointestinal and visceral organ changes were less common.
- Radiological findings can stem from mast cell infiltration or mediator effects.
Conclusions:
- Radiological changes in SMCD are not pathognomonic but are valuable.
- Imaging findings, combined with clinical data, assist in diagnosis and staging.
- Further investigations are guided by radiological evidence of systemic involvement.