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Updated: Aug 14, 2025

Humanized NOD/SCID/IL2rγnull (hu-NSG) Mouse Model for HIV Replication and Latency Studies
Published on: January 7, 2019
[Care and information for an HIV-positive patient]
Véronique Bellein1, Gaëlle Cornec1, Romain Le Menn1
1Consultations VIH, CHRU Morvan, 2 avenue Foch, 29200 Brest, France.
Abstract:
Since the year 2000, AIDS has become a chronic disease that can be treated and monitored. The two specific and necessary parameters for monitoring patients are the CD4 lymphocyte rate, which indicates the state of the immune system, and the viral load, which makes it possible to monitor the effectiveness of the antiretroviral treatments prescribed; in addition, blood antiretroviral drugs can be measured in certain cases. Today, it is clear that a patient who is effectively treated with an undetectable viral load is no longer a contaminant and that he or she will live with the disease, while facing the health issues common to everyone: emotional life, aging, other pathologies. Each caregiver, whether in the city or in a health care facility, will have a role to play in the care process.
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