Related Experiment Video
Updated: Aug 14, 2025
07:07
A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
12.5K
Practice Dilemma: Expanding Melanonychia in the Paediatric Setting
Cheng Huang1,2, Peter Bullpitt3, Mark Nabarrro4
1Department of Dermatology, St. George Hospital, Sydney, New South Wales, Australia.
Skin Appendage Disorders
|January 16, 2023
Summary
Diagnosing nail pigmentation in children is difficult. A case study found that a pigmented fingernail in an 11-year-old was benign lentigo with melanocyte hyperplasia, not melanoma.
Area of Science:
- Dermatology
- Paediatric Pathology
Background:
- Melanonychia diagnosis in children poses challenges due to the need for anesthesia for biopsies.
- Distinguishing benign from malignant nail pigmentation is crucial for appropriate management.
Related Concept Videos
01:30Skin Cancer
4.4K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.4K
01:05Accessory Structures of the Skin: Nails
1.8K
Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
The main components of a nail include the following.
Nail Plate: The nail plate is the visible portion of the nail that extends beyond the fingertips or toes. It is a hard, translucent...
1.8K
01:14Changes in Skin Color: Clinical Perspectives
2.0K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
2.0K
01:16Nails and Hair
Nails and HairNails and hair are more than just parts of our appearance; they are made of a strong protein called keratin and play important roles in protecting our bodies. Hair helps keep us warm and protects our skin from sunlight. Nails protect the tips of our fingers and toes and help us do everyday tasks like scratching or picking things up. Both nails and hair grow from special areas in our skin and can show signs of our health. Learning about nails and hair helps you understand how the...