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Related Concept Videos

Upper Respiratory Drugs: First and Second-Generation Antihistamines01:15

Upper Respiratory Drugs: First and Second-Generation Antihistamines

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Antihistamines are a class of drugs widely used to alleviate the symptoms of allergies, such as sneezing, itching, and nasal congestion. They work by inhibiting the actions of histamine, which is released by immune cells in response to allergenic substances or tissue injuries.
Histamine binds to specific receptor sites, known as H1 receptors, on tissue cells, triggering inflammation and swelling. Antihistamines combat these effects by competing with histamine for these receptor sites. By...
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Allergic Drug Reactions01:27

Allergic Drug Reactions

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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
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Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

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Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...
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Upper Respiratory Drugs: Decongestants01:27

Upper Respiratory Drugs: Decongestants

301
Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...
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Allergic Reactions02:06

Allergic Reactions

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Related Experiment Video

Updated: Aug 14, 2025

Author Spotlight: Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
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Cetirizine Hydrochloride Injection.

Danial E Baker1

  • 1Washington State University, Spokane, USA.

Hospital Pharmacy
|January 16, 2023
PubMed
Summary

The Formulary Monograph Service provides monthly drug monographs for Pharmacy & Therapeutics Committees, aiding in informed medication management and utilization reviews for healthcare facilities.

Area of Science:

  • Pharmaceutical Sciences
  • Health Services Research

Background:

  • Pharmacy & Therapeutics (P&T) Committees require timely, evidence-based drug information for formulary decisions.
  • Evaluating new and investigational drugs is crucial for optimizing medication use and patient safety.

Purpose of the Study:

  • To describe the content and utility of The Formulary Monograph Service.
  • To highlight the service's role in supporting P&T Committee functions and medication use evaluations.

Main Methods:

  • The service delivers 5-6 detailed monographs on new or late-phase drugs monthly.
  • Includes 1-page summaries for pharmacy and nursing in-services and comprehensive drug utilization/medication use evaluations (DUE/MUE).

Main Results:

  • Subscribers receive online access to monographs, which can be customized for facility needs.

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Last Updated: Aug 14, 2025

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  • Selected reviews are published in cooperation with Hospital Pharmacy.

    • Conclusions:

    • The Formulary Monograph Service offers a valuable resource for healthcare professionals.
    • It supports evidence-based formulary management and medication use evaluation processes.