Related Experiment Video
Updated: Aug 14, 2025

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
Risk factors associated with 1-week revisit among emergency department patients with alcohol withdrawal
Frank X Scheuermeyer1,2,3, Daniel Lane4, Brian Grunau5,6
1Department of Emergency Medicine, St Paul's Hospital and The University of British Columbia, Vancouver, BC, Canada. frank.scheuermeyer@gmail.com.
Insights
Approximately 15% of patients treated for alcohol withdrawal in the emergency department (ED) return within a week. Factors like prior ED visits, homelessness, high blood alcohol levels, and severe withdrawal symptoms increase this risk.
Area of Science:
- Emergency Medicine
- Addiction Psychiatry
- Public Health
Background:
- Alcohol withdrawal is a common reason for emergency department (ED) visits.
- A significant proportion of patients discharged after alcohol withdrawal treatment experience unscheduled return visits within one week.
- Predictors for these revisits remain incompletely understood.
Purpose of the Study:
- To identify patient and clinical factors associated with a high risk of 1-week ED revisits after discharge for alcohol withdrawal.
- To inform discharge planning and follow-up strategies for at-risk individuals.
Main Methods:
- Retrospective chart review of 935 ED visits for alcohol withdrawal across three urban EDs in Vancouver, Canada (2015-2018).
- Inclusion criteria: patients discharged with a primary or secondary diagnosis of alcohol withdrawal.
- Statistical analysis: Univariable and multivariable Bayesian binomial regression to identify factors associated with being in the upper quartile of 1-week ED revisits.
Main Results:
- The overall 1-week ED revisit rate was 15.0%.
- Factors independently associated with a high risk of revisit included: prior ED visit within 30 days, homelessness (no fixed address), initial blood alcohol level > 45 mmol/L, and initial Clinical Institute Withdrawal Assessment-alcohol revised (CIWA-Ar) score > 23.
- These identified factors explained 41% of the variance in revisit rates.
Conclusions:
- Specific patient and clinical factors are associated with increased 1-week ED revisits for alcohol withdrawal.
- Identifying high-risk patients can aid clinicians in developing targeted discharge plans and integrated follow-up support.
- Further research may explore interventions to reduce alcohol withdrawal-related ED revisits.
Background:
Approximately one-quarter of emergency department (ED) visits for alcohol withdrawal result in unscheduled 1-week ED return visits, but it is unclear what patient and clinical factors may impact this outcome METHODS: From January 1, 2015, to December 31, 2018, at three urban EDs in Vancouver, Canada, we studied patients who were discharged with a primary or secondary diagnosis of alcohol withdrawal. We performed a structured chart review to ascertain patient characteristics, ED treatments, and the outcome of an ED return within 1 week of discharge. We used univariable and multivariable Bayesian binomial regression to identify characteristics associated with being in the upper quartile of 1-week ED revisits.
Results:
We collected 935 ED visits among 593 unique patients. Median age was 45 years (interquartile range 34 to 55 years) and 71% were male. The risk of a 1-week ED revisit was 15.0% (IQR 12.3; 19.5%). After adjustment, factors independently associated with a high risk for return included any prior ED visit within 30 days, no fixed address, initial blood alcohol level > 45 mmol/L, and initial Clinical Institute Withdrawal Assessment-alcohol revised score > 23. These factors explained 41% of the overall variance in revisits.
Conclusion:
Among discharged ED patients with alcohol withdrawal, we describe high-risk patient characteristics associated with 1-week ED revisits, and these findings may assist clinicians to facilitate appropriate discharge planning with access to integrated follow-up support.
More Related Videos
08:05A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
Published on: January 5, 2018
05:40The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
Published on: April 28, 2022
Related Concept Videos
CNS Depressants: Alcohol and Nicotine
Drug Dependence
Substance Use Disorders Affecting Sleep
Understanding the concepts of physical dependence,...
Psychological and Sociocultural Causes of Schizophrenia
Stress Prevention and Stress Management Techniques IV
Drug Abuse and Addiction: Pharmacological Phenomena