Related Experiment Video
Updated: Aug 14, 2025

Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
Published on: January 23, 2018
Diffuse pigmented villonodular synovitis treated with arthroscopic total synovial peel.
Hao-Qiang Song1, Guo-Feng Wu2, Wei-Zhong Qi1
1Department of Joint and Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, People's Republic of China.
Arthroscopic total synovial peel (ATSP) offers a promising solution for diffuse pigmented villonodular synovitis (PVNS), significantly reducing recurrence rates. This innovative technique improves patient outcomes and knee function, making it a viable surgical option.
Area of Science:
- Orthopedic Surgery
- Musculoskeletal Oncology
- Arthroscopy
Background:
- Diffuse pigmented villonodular synovitis (PVNS) frequently recurs after surgical treatment.
- Achieving a complete and long-term cure for PVNS remains challenging.
Purpose of the Study:
- To introduce and evaluate the efficacy of arthroscopic total synovial peel (ATSP) for diffuse PVNS.
- To reduce the postoperative recurrence rate of diffuse PVNS.
Main Methods:
- Nineteen patients with diffuse PVNS of the knee underwent ATSP between March 2014 and July 2020.
- The ATSP technique involves a 'peeling' of the synovium, distinct from simple excision.
- Outcomes were assessed via imaging, recurrence rates, and functional scores (VAS, TLS) with a mean follow-up of 36 months.
Main Results:
- The study reported a recurrence rate of 10.5% following ATSP.
- Patients without recurrence showed significant improvements: VAS decreased from 4.76 to 1.56, and TLS increased from 67.76 to 90.32.
- ATSP demonstrated a significantly lower postoperative recurrence rate compared to existing literature.
Conclusions:
- Arthroscopic total synovial peel (ATSP) is a potentially effective arthroscopic treatment for diffuse PVNS.
- This technique shows promise in substantially reducing the recurrence of PVNS.
- ATSP warrants consideration as a viable clinical option for managing diffuse PVNS.
Related Concept Videos
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents

