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Acute Hormonal Responses to Multi-Joint Resistance Exercises with Blood Flow Restriction.

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Multi-joint resistance exercises with blood flow restriction show similar acute hormonal responses to high-load training. Growth hormone and IGFBP-3 levels significantly increased post-exercise in both protocols.

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Area of Science:

  • Exercise Physiology
  • Endocrinology
  • Sports Science

Background:

  • Hormonal responses to resistance exercise are crucial for adaptation.
  • Blood flow restriction (BFR) training is a novel method to potentially enhance these responses.
  • Understanding acute hormonal effects of BFR combined with multi-joint resistance exercises (MJRE) is important.

Purpose of the Study:

  • To investigate the acute hormonal responses to MJRE with and without BFR.
  • To compare the effects of low-intensity BFR (LI + BFR) versus high-intensity (HI) resistance exercise protocols.
  • To examine changes in growth hormone (GH), insulin-like-growth-factor-1-binding-protein-3 (IGFBP-3), testosterone, and cortisol.

Main Methods:

  • Ten men performed two randomized protocols: LI + BFR (20% 1RM, 30s rest) and HI (75% 1RM, 90s/30s rest).
  • Both protocols involved MJRE (half squat, chest press).
  • Blood samples were collected pre-exercise, immediately post-exercise, and 15 minutes post-exercise.

Main Results:

  • Significant increases in GH (2072-2278%) and IGFBP-3 (13-15%) were observed from pre to post-exercise for both protocols.
  • GH and IGFBP-3 showed time effects but no significant protocol differences.
  • No significant changes were found in total testosterone, free testosterone, or cortisol.

Conclusions:

  • MJRE combined with intermittent BFR elicits acute hormonal responses comparable to traditional high-load training.
  • LI + BFR may be a viable alternative for inducing acute hormonal changes.
  • Further research is needed to explore the chronic effects of LI + BFR with MJRE on muscle hypertrophy.