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Frontal intermittent rhythmic delta activity (FIRDA) in pial-dural arteriovenous malformation

S M Nazarian1, R E Potts, M Z Chesser

  • 1Neurology Service, John L. McClellan Memorial Veterans Hospital, Little Rock, Arkansas 72205.

Insights

Frontal intermittent rhythmic delta activity (FIRDA) can be linked to pial-dural arteriovenous malformations (AVMs). This case suggests AVMs, not just intracranial hypertension, may cause FIRDA, highlighting the need for thorough AVM investigation.

Area of Science:

  • Neurology
  • Neuroimaging
  • Vascular Neurology

Background:

  • Frontal intermittent rhythmic delta activity (FIRDA) is typically associated with frontal lobe ischemia or periventricular edema.
  • FIRDA has not been previously reported in association with benign intracranial hypertension (BIH).

Observation:

  • A patient presented with headaches, papilledema, and partial oculomotor nerve palsy.
  • Computed tomography (CT) scans failed to identify an underlying pial-dural arteriovenous malformation (AVM).
  • The patient exhibited FIRDA, which was initially considered in the context of presumed BIH.

Findings:

  • A pial-dural arteriovenous malformation (AVM) was identified as the cause of the patient's symptoms.
  • Partial embolization of the AVM led to the resolution of headaches, papilledema, and oculomotor nerve palsy.
  • Following AVM treatment, the FIRDA disappeared, supporting a causal link.

Implications:

  • This case suggests that circulatory "steal" effect from AVMs, rather than intracranial hypertension, may cause FIRDA.
  • It is recommended to diligently search for additional pathology, such as AVMs, when FIRDA is observed in patients with presumed BIH.
  • This finding expands the differential diagnosis for FIRDA and emphasizes the importance of comprehensive vascular evaluation.

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