Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Adaptation to exercise-induced muscle damage.

P M Clarkson1, W C Byrnes, E Gillisson

  • 1Department of Exercise Science, University of Massachusetts, Amherst 01003.

Clinical Science (London, England : 1979)
|October 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intermittent low dose carbon monoxide inhalation does not influence glucose regulation in overweight adults: a randomized controlled crossover trial.

Experimental physiology·2020
Same author

Is it Time to Change Radiotherapy: The Dawning of Chronoradiotherapy?

Clinical oncology (Royal College of Radiologists (Great Britain))·2019
Same author

Estimating Energy Expenditure using Individualized, Power-Specific Gross Efficiencies.

International journal of sports medicine·2016
Same author

Exercise and Serum Androgens in Women.

The Physician and sportsmedicine·2016
Same author

Ten Days of Intermittent, Low-dose Carbon Monoxide Inhalation does not Significantly Alter Hemoglobin Mass, Aerobic Performance Predictors, or Peak-power Exercise Tolerance.

International journal of sports medicine·2016
Same author

Acute, Low-dose CO Inhalation does not Alter Energy Expenditure during Submaximal Exercise.

International journal of sports medicine·2015
Same journal

HDAC9 promotes atherosclerosis by suppressing CYP7A1 and impairing hepatic cholesterol excretion.

Clinical science (London, England : 1979)·2026
Same journal

Clusterin ameliorates LPS-induced ARDS by inhibiting the Wnt/β-catenin pathway.

Clinical science (London, England : 1979)·2026
Same journal

Human cytomegalovirus at the maternal-fetal interface: an overview of pathogenesis, defence, and interventions.

Clinical science (London, England : 1979)·2026
Same journal

Cardiometabolic regulation by adipocyte-derived leptin and the brain melanocortin system.

Clinical science (London, England : 1979)·2026
Same journal

Impact of impaired branched-chain amino acid metabolism on kidney disease.

Clinical science (London, England : 1979)·2026
Same journal

Ex vivo pretreatment of donor organ with siRNA nanoparticles attenuates cold ischemia-reperfusion injury in cardiac transplantation.

Clinical science (London, England : 1979)·2026
See all related articles

Eccentric exercise causes muscle damage, indicated by creatine kinase (CK) and soreness. Repeating exercise on the same limb shows adaptation, but not on the opposite limb, suggesting localized muscle adaptation.

Area of Science:

  • Exercise physiology
  • Muscle adaptation
  • Sports science

Background:

  • Muscle damage from eccentric exercise is common.
  • Indicators include serum creatine kinase (CK) and muscle soreness.
  • Understanding muscle adaptation is key for training and injury prevention.

Purpose of the Study:

  • To examine rapid muscle adaptation using the ipsilateral limb in a second bout of exercise.
  • To investigate potential central adaptations when the contralateral limb is exercised in a second bout.
  • To compare the 'repeat bout effect' between ipsilateral and contralateral limbs.

Main Methods:

  • 16 subjects performed two bouts of eccentric exercise, 7 days apart.
  • The LSL group (n=7) exercised the ipsilateral limb in both bouts.

Related Experiment Videos

  • The LOL group (n=9) exercised the contralateral limb in the second bout, with stabilization to isolate the limb.

    • Main Results:

    • The LSL group showed reduced CK and soreness in bout 2 compared to bout 1, indicating adaptation.
    • The LOL group exhibited no significant difference in CK or soreness between bout 1 and bout 2.
    • No significant 'repeat bout effect' was observed in the contralateral limb, suggesting minimal central adaptation.

    Conclusions:

    • Rapid muscle adaptation occurs locally within the exercised (ipsilateral) limb.
    • Central adaptations contributing to reduced muscle damage are minimal when the contralateral limb is exercised.
    • An experimental design using ipsilateral muscle groups is effective for studying rapid exercise-induced muscle adaptation.