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MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
Published on: September 3, 2013
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Novel PSMA-Targeting Radionuclide Peptidomimetics for Treating Prostate Cancer
1Experimental Drug Development Centre. 10 Biopolis Road, Chromos #08-01, Singapore 138670, Singapore.
ACS Medicinal Chemistry Letters
|January 19, 2023
Summary
Lutetium Lu 177 vipivotide tetraxetan is a novel targeted radionuclide therapy for metastatic castration-resistant prostate cancer. This study highlights its structure-activity relationship against prostate cancer cells, offering new treatment avenues.
Area of Science:
- Oncology
- Radiopharmaceutical Therapy
- Medicinal Chemistry
Background:
- Prostate cancer is a leading cause of cancer death in men globally.
- Treatment options are limited for patients with resistance to taxane chemotherapeutics.
- Metastatic castration-resistant prostate cancer (mCRPC) presents significant therapeutic challenges.

