Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cone-mediated retinal function in cats during development.

S G Jacobson1, H Ikeda, K Ruddock

  • 1Bascom Palmer Eye Institute, University of Miami School of Medicine, FL 33136.

Documenta Ophthalmologica. Advances in Ophthalmology
|January 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Purification and characterization of DNA topoisomerase IV in Escherichia coli.

The Journal of biological chemistry·1992
Same author

Prognostic factor of telecobalt therapy for early glottic carcinoma.

Cancer·1992
Same author

[Adult T-cell leukemia with various pulmonary complications].

Nihon Kyobu Shikkan Gakkai zasshi·1992
Same author

Sulfur amino acid levels and related enzyme activities in various brain regions (and other tissues) in normal mice and rolling mice Nagoya.

Acta medica Okayama·1992
Same author

[Adult T-cell leukemia/lymphoma, histologically presenting Ki-1 positive anaplastic large cell lymphoma].

[Rinsho ketsueki] The Japanese journal of clinical hematology·1992
Same author

Phase I/II study of high-dose rate interstitial radiotherapy for head and neck cancer.

Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]·1992
Same journal

The relationship between foveal anatomy and retinal function in oculocutaneous albinism.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Early onset primary angle closure and foveal retinoschisis associated with a pseudo-homozygous CRB1 pathogenic variant.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Bilateral perifoveal macular ischemia in non-proliferative Duchenne muscular dystrophy-associated retinopathy: a case report.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Association between dynamic pupil parameters and corneal sub-basal nerve plexus morphology.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Structure-function relationship between handheld photopic negative response and macular GCIPL thickness in chronic optic neuropathy.

Documenta ophthalmologica. Advances in ophthalmology·2026
Same journal

Clinical course of a patient with PRSS56-associated nanophthalmos (isolated microphthalmia) and uveal effusion syndrome.

Documenta ophthalmologica. Advances in ophthalmology·2026
See all related articles

Kitten cone electroretinograms (ERGs) show that cone function matures later than rod function. Cone b-wave amplitudes are adult-like by 100 days, but timing normalizes after 80 days.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Developmental Biology

Background:

  • Retinal function development is crucial for visual perception.
  • Understanding the maturation timeline of cone photoreceptors is essential for diagnosing visual impairments.
  • Previous studies suggest differential development rates between cone and rod systems in cats.

Purpose of the Study:

  • To investigate the developmental trajectory of cone-mediated electroretinogram (ERG) responses in kittens.
  • To compare the maturation timelines of cone ERG amplitude and implicit time with adult cats.
  • To determine the age at which critical flicker fusion frequency (CFFF) matures in feline cone vision.

Main Methods:

  • Cone electroretinograms (ERGs) were recorded in kittens aged 25 to 150 days and adult cats.

Related Experiment Videos

  • Single flash cone ERG b-wave amplitude and implicit time were analyzed.
  • 40-Hz flicker ERGs were used to confirm single flash cone ERG findings.
  • Critical flicker fusion frequency (CFFF) was measured to assess visual processing speed.

    • Main Results:

    • Kitten cone b-wave amplitudes were within or exceeded adult ranges between 25 and 94 days, reaching adult-like levels by approximately 100 days.
    • Cone b-wave implicit time was significantly prolonged in younger kittens, normalizing to adult values after 80 days of age.
    • 40-Hz flicker ERG data and CFFF measurements (mature by 74 days) corroborated the single flash cone ERG findings.
    • These results indicate distinct developmental timelines for cone-mediated retinal function.

    Conclusions:

    • Feline cone visual system development exhibits a protracted maturation process, particularly concerning response timing.
    • Cone b-wave amplitude maturation precedes the normalization of cone response timing.
    • These findings highlight the differential development of cone and rod retinal functions in cats, with cones maturing later in terms of response kinetics.