Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

27
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
27
Autoimmune Disorders01:29

Autoimmune Disorders

593
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
593
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

43
The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
43
Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

13.8K
Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
13.8K
T Cell Types and Functions01:24

T Cell Types and Functions

1.2K
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
1.2K
Cross-reactivity00:42

Cross-reactivity

31.4K
Overview
31.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

First profiling of the national Swiss Clinical Quality Management giant cell arteritis and polymyalgia rheumatica registry.

Clinical and experimental rheumatology·2026
Same author

Ultrasound-guided injection of the rotator interval synovial lining: A cadaveric validation.

Shoulder & elbow·2025
Same author

Imaging to predict early relapses after treatment discontinuation in patients with large vessel giant cell arteritis - A cohort study.

Seminars in arthritis and rheumatism·2024
Same author

Prior polymyalgia rheumatica is associated with sonographic vasculitic changes in newly diagnosed patients with giant cell arteritis.

Rheumatology (Oxford, England)·2023
Same author

Correction to: Immunologic and Genetic Contributors to CD46‑Dependent Immune Dysregulation.

Journal of clinical immunology·2023
Same author

Immunologic and Genetic Contributors to CD46-Dependent Immune Dysregulation.

Journal of clinical immunology·2023

Related Experiment Video

Updated: Aug 13, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

304

[Reactive arthritis].

Mihaela Stegert1

  • 1Klinik für Rheumatologie, Universitätsspital Basel, Schweiz.

Therapeutische Umschau. Revue Therapeutique
|January 20, 2023
PubMed
Summary

Reactive arthritis is an inflammatory condition often following a bacterial infection. Treatment focuses on antibiotics for the trigger infection and NSAIDs for joint inflammation, though some cases require long-term therapy.

Area of Science:

  • Rheumatology
  • Immunology
  • Infectious Disease

Context:

  • Reactive arthritis is a sterile, inflammatory arthritis.
  • It typically follows a bacterial gastrointestinal or urogenital infection.
  • The onset is usually one to four weeks post-infection.

Purpose:

  • To outline the characteristics, triggers, and management of reactive arthritis.
  • To describe the clinical presentation and extra-articular manifestations.
  • To discuss the prognosis and therapeutic strategies.

Summary:

  • Presents as asymmetric oligoarthritis, predominantly affecting lower extremities.
  • Can involve enthesitis, dactylitis, sacroiliitis, and extra-articular signs like conjunctivitis and uveitis.
  • Antibiotics for triggering infections (e.g., Chlamydia trachomatis), NSAIDs, glucocorticosteroids, and DMARDs are used for treatment.

More Related Videos

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

282
Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
09:18

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue

Published on: February 24, 2023

8.0K

Related Experiment Videos

Last Updated: Aug 13, 2025

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain
04:50

Preliminary Study on Acupuncture Combined with Grain-sized Moxibustion for Treating Rheumatoid Arthritis with Finger Joint Pain

Published on: May 16, 2025

304
An Adoptive Transfer Model of Rheumatoid Arthritis in Mice
07:37

An Adoptive Transfer Model of Rheumatoid Arthritis in Mice

Published on: June 6, 2025

282
Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue
09:18

Author Spotlight: Isolation and Culture of Primary Synovial Macrophages and Fibroblasts from Murine Arthritis Tissue

Published on: February 24, 2023

8.0K

Impact:

  • Over 50% of patients experience a self-limited course of 2-6 months.
  • 30% have recurrent episodes, while 10-20% develop a chronic condition needing immunosuppression.
  • Understanding these patterns guides appropriate patient management and prognosis assessment.