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Acute pancreatitis after nitrous oxide abuse: A case report
Shanshan Chen1, Linjie Guo2, Yufang Wang2
1West China School of Medicine, Sichuan University Chengdu China.
JGH Open : an Open Access Journal of Gastroenterology and Hepatology
|January 20, 2023
Summary
Recreational nitrous oxide (N2O) abuse is rising, and can lead to severe health issues. This case highlights acute pancreatitis as a rare but serious complication of N2O intoxication in young adults.
Area of Science:
- Toxicology
- Gastroenterology
- Neurology
Background:
- Recreational nitrous oxide (N2O) use is increasing among young adults.
- N2O abuse can lead to severe health complications.
- The link between N2O and acute pancreatitis is seldom reported.
Observation:
- A previously healthy young female presented with cutaneous lesions, neurological symptoms, and abdominal pain.
- Acute pancreatitis was the initial diagnosis.
- N2O intoxication was diagnosed after uncovering a history of one-month N2O abuse.
Findings:
- Acute pancreatitis can be a rare complication of nitrous oxide intoxication.
- Mecobalamin and symptomatic treatments led to gradual improvement in symptoms and laboratory markers.
Implications:
- Clinicians should consider N2O intoxication in young adults presenting with acute pancreatitis, especially with neurological or cutaneous symptoms.
- Increased awareness of N2O's potential to induce pancreatitis is crucial for early diagnosis and management.
- This case underscores the importance of thorough patient history in identifying substance abuse related to rare medical presentations.
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