Related Experiment Video
Updated: Aug 13, 2025

Establishment of a Mouse Severe Acute Pancreatitis Model using Retrograde Injection of Sodium Taurocholate into the Biliopancreatic Duct
Published on: April 1, 2022
Acute pancreatitis after nitrous oxide abuse: A case report
Shanshan Chen1, Linjie Guo2, Yufang Wang2
1West China School of Medicine, Sichuan University Chengdu China.
Abstract:
The recreational use of nitrous oxide (N2O) is sharply increasing among young adults. N2O abuse can cause serious complications. However, the association between acute pancreatitis and N2O is rarely reported. Here we report a case of a young and previously healthy female with widespread cutaneous lesions, neurologic symptoms, and abdominal pain. Acute pancreatitis was the patient's primary diagnosis when she was admitted to the gastroenterology unit. We added the diagnosis of N2O intoxication after an additional inquiry into the patient's personal history revealed that she had abused N2O for 1 month. With the application of mecobalamin and other symptomatic treatments, the symptoms and laboratory indexes improved gradually. In this case, we highlight that acute pancreatitis may be a rare complication induced by N2O.
Related Concept Videos
Acute Pancreatitis II: Clinical Manifestations and Management
Acute Pancreatitis I: Introduction
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
2° Amines to N-Nitrosamines: Reaction with NaNO2
Chronic Pancreatitis I: Introduction
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis II: Collaborative Care
Assessment:
Acute Respiratory Failure-III

