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Persistent Asthma at School Age: Associated Factors in Preschool Children with Asthma

Kantisa Sirianansopa1, Kanokpan Ruangnapa1, Pharsai Prasertsan1

  • 1Division of Pulmonology, Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, 15 Karnjanavanich Road, Hatyai 90110, Songkhla, Thailand.

Children (Basel, Switzerland)
|January 21, 2023
PubMed

Insights

Early identification of childhood asthma risks is key. Breastfeeding protects against persistent asthma, while siblings and industrial areas increase risk, highlighting targets for prevention.

Area of Science:

  • Pediatric Allergy and Immunology
  • Respiratory Medicine
  • Epidemiology

Background:

  • Childhood asthma often manifests in preschool years, necessitating early identification of risk and protective factors.
  • Understanding these factors is crucial for developing effective asthma prevention and control strategies in young children.

Purpose of the Study:

  • To identify preschool-age factors associated with persistent asthma at school age.
  • To inform early intervention strategies for preventing long-term asthma.

Main Methods:

  • Retrospective observational study of 189 preschool children with asthma (2015-2020) at a university hospital in Southern Thailand.
  • Analysis of wheeze characteristics, breastfeeding, household factors, environmental exposures, and comorbidities.

Main Results:

  • Approximately 20% of participants had persistent asthma.
  • Breastfeeding demonstrated a protective effect (OR 0.4).
  • Risk factors included siblings in the household (OR 2.6), industrial area residence (OR 3.8), and allergic rhinitis (OR 3.6).

Conclusions:

  • Early breastfeeding is a protective factor against persistent asthma.
  • Siblings, industrial area living, and allergic rhinitis are significant risk factors.
  • Targeting modifiable factors in preschool children offers a critical opportunity for asthma prevention.

Keywords:
environmental risk factorsmodifiable risk factorspersistent asthmapreschool asthmaprotective factors

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