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Published on: December 8, 2015
Plain metallic biomaterials: opportunities and challenges
Jiazhen Zhang1, Bao Zhai1, Jintao Gao2
1Center for Medical Device Evaluation, National Medical Product Administration, Beijing 100081, China.
Abstract:
The 'plainification of materials' has been conceptualized to promote the sustainable development of materials. This perspective, for the first time in the field of biomaterials, proposes and defines 'plain metallic biomaterials (PMBs)' with demonstrated research and application case studies of pure titanium with high strength and toughness, and biodegradable, fine-grained and high-purity magnesium. Then, after discussing the features, benefits and opportunities of PMBs, the challenges are analyzed from both technical and regulatory aspects. Regulatory perspectives on PMB-based medical devices are also provided for the benefit of future research, development and commercialization.
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