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Updated: Aug 13, 2025
Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Foveal avascular zone in normal human eyes by optical coherence tomography angiography
Yunlei Pang1, Guoqiang Zhang2, Han Zhang3
1Department of ophthalmology, Chifeng Chaoju Eye Hospital, Chifeng, 024000, China.
Objective:
To analyze the influence factors of the area of superficial plexus foveal avascular zone (FAZ) and related indexes of fovea measured with optical coherence tomography angiography (OCT-A) in normal subjects.
Methods:
This was a cross-sectional study from November 2020 to May 2021 in the Inner Mongolia Autonomous Region, China. Each subject received related eye examination. The correlation between all the factors and superficial plexus FAZ were analyzed under univariable and multivariable linear regression analysis.
Results:
Finally, 239 subjects with sufficient data were recruited in the study, including 108 males and 131 females, aged 27.41±4.63 years. The area of superficial plexus FAZ was 0.33±0.16 mm2. In the univariate regression, gender (β = 41.702, 95%CI: 9.152 to 74.253, P = 0.012), drinking (β = -66.074, 95%CI: -99.197 to -32.951, P = 0.001) and axial length (β = -15.874, 95%CI: -29.562 to -2.185, P = 0.023) were associated with superficial plexus FAZ area. In multivariate regression analysis results, drinking (β = -42.410, 95%CI = -79.388 to -5.432, P = 0.025) was significantly correlated with superficial plexus FAZ area.
Conclusion:
The area of superficial plexus FAZ was not affected by age, gender, systematical and biochemical indicators, but related to the status of drinking.
