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Geometric Morphometrics Can Predict Postoperative Visual Acuity Changes in Patients With Epiretinal Membrane: A
Sugao Miyagi1, Akio Oishi1, Eiko Tsuiki1
1Department of Ophthalmology and Visual Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, Japan.
Translational Vision Science & Technology
|January 24, 2023
Summary
Geometric morphometrics effectively assesses retinal deformation in epiretinal membrane (ERM) patients. This method predicts surgical outcomes, offering a novel approach to evaluating ERM severity and treatment efficacy.
Area of Science:
- Ophthalmology
- Medical Imaging
- Biomedical Engineering
Background:
- Epiretinal membrane (ERM) causes retinal distortion, impacting visual acuity.
- Current methods for assessing ERM severity have limitations.
Purpose of the Study:
- Evaluate the efficacy of geometric morphometrics for assessing retinal deformation in ERM.
- Determine if deformation degree predicts postoperative visual outcomes.
Main Methods:
- Retrospective analysis of 29 ERM patient eyes and their fellow eyes.
- Comparison of optical coherence tomography (OCT) images using geometric morphometrics (thin-plate spline).
- Measurement of conventional OCT parameters and correlation with visual acuity.
Main Results:
- Geometric morphometrics-derived bending energy correlated significantly with visual acuity.
- Bending energy was an independent predictor of postoperative visual acuity changes.
- Bending energy showed association with conventional OCT parameters.
Conclusions:
- Geometric morphometrics is effective for evaluating ERM severity.
- This method can predict surgical outcomes in ERM patients.
