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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

31
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
31
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

39
Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

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Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
49
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

54
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
54
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

51
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
51
Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

66
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
66

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Updated: Aug 12, 2025

Microdissection of Primary Renal Tissue Segments and Incorporation with Novel Scaffold-free Construct Technology
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Kidney organ allocation: reducing discards.

John J Friedewald1, Karolina Schantz2, Sanjay Mehrotra2

  • 1Northwestern University Feinberg School of Medicine, Chicago.

Current Opinion in Organ Transplantation
|January 25, 2023
PubMed
Summary
This summary is machine-generated.

Each year, up to 20% of donated kidneys in the US are discarded due to various factors, despite high demand for kidney transplants. This review examines the causes of kidney discard and proposes solutions to improve organ utilization.

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Area of Science:

  • Nephrology
  • Transplantation Medicine
  • Public Health Policy

Background:

  • The United States kidney transplant system faces a critical challenge in reducing the discard rate of procured kidneys.
  • Approximately 20% of donated kidneys are discarded annually, exacerbating the shortage for patients awaiting transplants.

Approach:

  • This review synthesizes current data on the multifaceted reasons behind high kidney discard rates.
  • Potential strategies and solutions to mitigate kidney discard are explored.

Key Points:

  • Multiple factors contribute to the discarding of viable donor kidneys.
  • Addressing these causes is crucial for optimizing the use of available organs.
  • Improving organ utilization can help meet the overwhelming demand for kidney transplants.

Conclusions:

  • Reducing kidney discard rates is essential for enhancing the efficiency and effectiveness of the organ donation and transplantation system.
  • Implementing proposed solutions could significantly increase the number of successful kidney transplants performed.