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Tooth Germ Autotransplantation With 24 Months of Follow-up: A Case Report
Luigi Tagliatesta1, Federico Guerri2, Anna Paola Iannone3
1Specialist in Oral Surgery, Unit of Oral Surgery, Department of Health Sciences, Santi Paolo and Carlo Hospital, University of Milan, Milan, Italy.
Summary
Autotransplantation of a third molar is a viable option for replacing missing teeth, especially in young patients. This case report shows successful tooth replacement with preserved vitality and root development after 24 months.
Area of Science:
- Dentistry
- Oral Surgery
- Regenerative Dentistry
Background:
- Autotransplantation of third molars offers a biological solution for replacing missing teeth, particularly in young individuals.
- This procedure can preserve periodontal health, maintain pulp vitality, and facilitate root development.
- Indications include traumatic avulsion, agenesis, or extensive caries leading to tooth loss.
Observation:
- A case report details the autotransplantation of an immature (open-apex) maxillary third molar germ.
- The donor tooth was used to replace a non-viable mandibular first molar in a growing patient.
- The procedure aimed to restore function and aesthetics while promoting natural tooth development.
Findings:
- After 24 months, the transplanted tooth exhibited normal physiological mobility.
- There were no signs of infection or ankylosis, and pulp vitality was confirmed.
- Radiographic evidence showed complete periodontal integration and significant root development (radicular edification).
Implications:
- Autotransplantation of immature third molars is a predictable and effective treatment for young patients requiring tooth replacement.
- This technique supports the maintenance of a healthy periodontium and natural root formation.
- It presents a valuable alternative to conventional prosthetic or implant solutions in specific clinical scenarios.

