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Correlation between serum vitamin D level and benign paroxysmal positional vertigo recurrence.
Hyun-Il Shin1, Yesai Park2, Hyun Jin Lee2
1Department of Otorhinolaryngology, The Catholic University of Korea, College of Medicine, Seoul St. Mary's Hospital, Seoul, Republic of Korea.
Auris, Nasus, Larynx
|January 25, 2023
Summary
Low vitamin D levels are linked to recurrent benign paroxysmal positional vertigo (BPPV). Monitoring vitamin D may help identify patients at higher risk for BPPV episodes.
Area of Science:
- Otolaryngology
- Neurology
- Endocrinology
Background:
- Benign paroxysmal positional vertigo (BPPV) is a prevalent cause of dizziness.
- Previous research suggests a connection between BPPV and serum vitamin D levels.
Purpose of the Study:
- To investigate the association between serum vitamin D levels and the recurrence of BPPV.
- To identify potential cut-off values for vitamin D that may predict BPPV recurrence.
Main Methods:
- Retrospective chart review of 50 patients diagnosed with BPPV (posterior and lateral canal).
- Classification into BPPV recurrence (Group A) and non-recurrence (Group B) groups.
- Assessment of otolith function using cVEMP and oVEMP, and evaluation of their relation to vitamin D levels.
Main Results:
- Lower average serum vitamin D levels were observed in the BPPV recurrence group (12.9 ng/mL) compared to the non-recurrence group (19.2 ng/mL) (p=0.011).
- An optimal cut-off value of 12.74 ng/mL for serum vitamin D was identified to predict BPPV recurrence.
- Patients with serum vitamin D below 12.74 ng/mL exhibited a significantly higher recurrence rate (70.5% vs. 22.5%, p=0.007).
Conclusions:
- Serum vitamin D levels are significantly associated with BPPV recurrence.
- Measuring serum vitamin D is important for monitoring and evaluating patients at risk of BPPV recurrence.

