Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Alcohols from Carbonyl Compounds: Reduction

Alcohols from Carbonyl Compounds: Reduction

Reduction is a simple strategy to convert a carbonyl group to a hydroxyl group. The three major pathways to reduce carbonyls to alcohols are catalytic hydrogenation, hydride reduction, and borane reduction.
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...

Acid Halides to Alcohols: LiAlH4 Reduction

Acid Halides to Alcohols: LiAlH₄ Reduction

Acid halides are reduced to alcohols in the presence of a strong reducing agent like lithium aluminum hydride.
The mechanism proceeds in three steps. First, the nucleophilic hydride ion attacks the carbonyl carbon of the acid halide to form a tetrahedral intermediate. Next, the carbonyl group is re-formed, and the halide ion departs as a leaving group, generating an aldehyde. A second nucleophilic attack by the hydride yields an alkoxide ion, which, upon protonation, gives a primary alcohol as...

Multiple Halogenation of Methyl Ketones: Haloform Reaction

Multiple Halogenation of Methyl Ketones: Haloform Reaction

A method involving the transformation of methyl ketones to carboxylic acids using excess base and halogen is called the haloform reaction. It begins with the deprotonation of α hydrogen to form an enolate ion which reacts with the electrophilic halogen to give an α-halo ketone. The step continues until all the α protons are substituted to form a trihalomethyl ketone. The resulting molecule is unstable, and in the presence of a hydroxide base, it readily undergoes nucleophilic...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

In situ Generation of Fluoride Catalysts for CO<sub>2</sub>-to-Formic Acid Conversion With Silicon Reducing Agent.

Chemistry (Weinheim an der Bergstrasse, Germany)·2026

Same author

Quantitative and Morphometric Measures in the Human Hippocampal Tail Using Ex Vivo Imaging Validated With Histology.

Hippocampus·2026

Same author

Toward Skin-like Sensors: Stretchable Conductive Gels for Triboelectric Applications.

Gels (Basel, Switzerland)·2026

Same author

Effect of immobilized amine structure on the formation and catalysis of Pd nanoparticles for oxidation of alcohols.

Chemical communications (Cambridge, England)·2026

Same author

CMR-FT right atrial strain is a novel predictive indicator in left ventricular noncompaction patients: a multi-center study.

Journal of translational medicine·2025

Same author

Insight into Interparticle Hydrogen Spillover Driven by Remote Metal Oxides.

ACS applied materials & interfaces·2025

Search research articles

Related Experiment Video

Updated: Aug 12, 2025

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

CO₂ conversion to formamide using a fluoride catalyst and metallic silicon as a reducing agent.

Ruopeng Wang¹, Kaiki Nakao^1,2, Yuichi Manaka^2,3

¹Department of Chemistry and Life Sciences, Yokohama National University, 79-5 Tokiwadai, Hodogaya-ku, Yokohama, 240-8501, Japan.

Communications Chemistry

|January 25, 2023

Summary

Metallic silicon from solar panels efficiently converts amines into amides using CO2 and water. This eco-friendly method offers a sustainable alternative for chemical synthesis and resource utilization.

More Related Videos

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

Published on: October 18, 2019

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Published on: November 27, 2015

Related Experiment Videos

Last Updated: Aug 12, 2025

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Versatile CO2 Transformations into Complex Products: A One-pot Two-step Strategy

Published on: November 9, 2019

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry

Published on: October 18, 2019

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Reverse Microemulsion-mediated Synthesis of Monometallic and Bimetallic Early Transition Metal Carbide and Nitride Nanoparticles

Published on: November 27, 2015

Area of Science:

Materials Science
Green Chemistry
Catalysis

Background:

Metallic silicon is a potential low-cost reducing agent for CO2 functionalization.
Conventional reducing agents like hydrogen and hydrosilanes have limitations.

Purpose of the Study:

To utilize metallic silicon from solar panel waste as a reducing agent for formamide synthesis.
To explore a novel catalytic system for efficient CO2 conversion.

Main Methods:

Formamide synthesis using metallic silicon, CO2, H2O, and tetrabutylammonium fluoride catalyst.
Characterization using in situ FTIR, XPS, XRD, and N2 adsorption/desorption.
Isotopic labeling experiments to elucidate reaction mechanisms.

Main Results:

Various amines were successfully converted to amides with CO2 and H2O.
Metallic silicon facilitated the reaction via an Si-H intermediate.
The fluoride catalyst promoted silicon oxidation and generated mesoporous materials with high surface area.

Conclusions:

Metallic silicon is an effective and sustainable reducing agent for formamide synthesis.
The catalytic system demonstrates broad substrate scope and potential for other reductive reactions.
This approach offers a strategy for efficient utilization of abundant resources and waste materials.