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Updated: Aug 12, 2025
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
ONCOCYTIC ADRENOCORTICAL CARCINOMA IN A YOUNG PATIENT
Y Singh1,2, J N Bharti1,2, G R Chaoudhary1,2
1Department of Pathology, All India Institute of Medical Sciences, Jodhpur, India.
Context:
Adrenocortical carcinoma (ACC) is a rare neoplasm with an aggressive course and poor prognosis. The worldwide incidence is about 0.5 to 2 cases per million population per year. Oncocytic adrenocortical carcinoma is a rare histopathological variant of ACC with only a few reported cases in the literature.
Case Report:
We report a case of an oncocytic variant of adrenocortical carcinoma in a 21-year-old male patient who presented with a left adrenal mass. Imaging studies confirmed a large left adrenal mass with involvement of the left renal vein and inferior vena cava. Endocrine workup showed mildly elevated serum cortisol levels.
Discussion:
Oncocytic AAC is a rare histopathological variant of ACC, as well as a rare subgroup of oncocytic adrenal neoplasms Hormonally active or functioning adrenocortical carcinomas most commonly secrete cortisol whereas co-secretion of multiple steroid hormones is a rare phenomenon.
Conclusions:
Surgery remains the mainstay of treatment, but most of the patients present late with large masses and eventually become unsuitable for curative resection.
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