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Screening for MAFLD: who, when and how?

Shreya C Pal^1,2, Nahum Méndez-Sánchez^3,1

¹Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.

Therapeutic Advances in Endocrinology and Metabolism

|January 26, 2023

Summary

Metabolic-associated fatty liver disease (MAFLD) is a growing global health issue. Universal, non-invasive screening using blood tests, imaging, and clinical data is crucial for early detection in at-risk individuals.

Keywords:

MAFLD diagnosis fatty liver screening

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Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease

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Published on: March 24, 2023

Area of Science:

Hepatology
Metabolic Disorders
Public Health

Background:

Metabolic-associated fatty liver disease (MAFLD) is a prevalent condition with rising global incidence.
MAFLD encompasses a spectrum from simple steatosis to hepatocellular carcinoma, posing significant health risks.
Extra-hepatic manifestations of MAFLD include cardiovascular diseases, malignancies, and cognitive/respiratory issues.

Purpose of the Study:

To emphasize the need for standardized, universal screening methods for MAFLD.
To highlight the importance of early identification of high-risk populations with metabolic dysfunction.

Main Methods:

Proposing universal non-invasive screening strategies.
Utilizing blood tests for metabolic assessment.
Employing imaging techniques like ultrasound.
Leveraging clinical information and scoring systems from patient-physician interactions.

Main Results:

Current lack of standardized screening methods for MAFLD.
MAFLD's broad impact on hepatic and extra-hepatic systems.
The potential of combined non-invasive methods for effective screening.

Conclusions:

Timely identification of individuals at high risk for MAFLD is essential.
Non-invasive screening approaches, integrating various data sources, are feasible and necessary.
Standardized screening protocols are needed to manage the growing burden of MAFLD.