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Willingness to Pay for Down Syndrome Screening: A systematics Review
Shima Nikjoo1, Aziz Rezapour2, Najmeh Moradi3
1Department of Health Economics, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
Medical Journal of the Islamic Republic of Iran
|January 26, 2023
Summary
Willingness to pay for Down syndrome (DS) screening varies significantly by country. Factors like income, education, and test accuracy influence how much women will pay for DS screening tests.
Area of Science:
- Healthcare Economics
- Medical Genetics
- Public Health
Background:
- Financial accessibility is crucial for healthcare services, necessitating adequate government funding.
- Understanding household willingness to pay (WTP) for specific services is essential.
- This review focuses on WTP for Down syndrome (DS) screening and its influencing factors.
Purpose of the Study:
- To systematically review existing literature on WTP for DS screening.
- To identify key factors influencing WTP for DS screening.
Main Methods:
- Systematic search of Scopus, PubMed, Web of Sciences, and Embase databases (inception to Dec 2021).
- Inclusion of 5 eligible studies published between 2005 and 2020 after full-text review.
- Standardized conversion of WTP values to USD (2018) and quality assessment using established checklists.
Main Results:
- WTP for DS screening ranged from $169 (UK) to $1118 (Canada) across reviewed studies.
- Income and knowledge about screening tests were the most studied factors influencing WTP.
- Higher WTP was associated with increased education, higher detection rates, maternal age, cost, and family history.
Conclusions:
- A notable disparity exists in WTP for DS screening globally.
- Women's WTP increases for tests with higher screening accuracy.
- Income, occupation, information access, family history, and maternal age significantly impact WTP for DS screening.

