Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mortality from asthma in Western Australia.

A W Musk1, G F Ryan, D M Perera

  • 1Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Queen Elizabeth II Medical Centre, Nedlands, WA.

The Medical Journal of Australia
|November 2, 1987
PubMed
Summary

Asthma patients face significantly higher mortality risks from asthma, chronic airflow obstruction, and ischemic heart disease. These findings highlight asthma as a potentially fatal condition requiring ongoing medical attention.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Dust diseases in modern Australia: a discussion of the new TSANZ position statement on respiratory surveillance.

The Medical journal of Australia·2021
Same author

Asbestos-related diseases.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2020
Same author

Measurement of urinary 1-aminopyrene and 1-hydroxypyrene as biomarkers of exposure to diesel particulate matter in gold miners.

The Science of the total environment·2019
Same author

Comment on: "Low-dose computed tomography screening for lung cancer in people with workplace exposure to asbestos".

Lung cancer (Amsterdam, Netherlands)·2019
Same author

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

American journal of human genetics·2018
Same author

Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.

European journal of cancer (Oxford, England : 1990)·2018

Area of Science:

  • Respiratory Medicine
  • Epidemiology
  • Public Health

Background:

  • Asthma is a chronic respiratory condition affecting millions globally.
  • Understanding long-term mortality risks associated with asthma is crucial for public health management.

Purpose of the Study:

  • To investigate the mortality risks associated with asthma in a large patient cohort.
  • To identify specific causes of death and age-related trends in asthma patients.

Main Methods:

  • Retrospective cohort study analyzing hospital discharge data from Western Australia (1976-1980).
  • Follow-up data collected until 1982 to identify all-cause and cause-specific mortality.
  • Calculation of Standardized Mortality Ratios (SMR) to compare observed deaths against expected rates.

Related Experiment Videos

Main Results:

  • A cohort of 10,739 asthma patients (5760 male, 4979 female) was analyzed.
  • Significantly elevated all-cause mortality was observed in both men (SMR 1.6) and women (SMR 1.7).
  • Increased mortality was linked to asthma (SMR 57.9), chronic airflow obstruction (SMR 9.3), and ischemic heart disease (SMR 1.3), with excess asthma deaths across all ages.

Conclusions:

  • Asthma is associated with a substantially increased risk of premature death from asthma itself and related conditions.
  • Chronic airflow obstruction and ischemic heart disease contribute to excess mortality in asthma patients, particularly in older age groups.
  • The findings underscore the potentially fatal nature of asthma and suggest a link between asthma and irreversible airflow obstruction.